Clarithromycin tablets may be given with or without food.
Adults: 250 mg every 12 hours for 7 days, increased in severe infections to 500 mg every 12 hours for up to 14 days. In patients with renal impairment with creatinine clearance < 30 ml/min, the dosage should be reduced by half. Dosage should not be continued beyond 14 days in these patients.